Targeted drug delivery under MRI guidance

Advances in Targeted Drug Delivery

Advances in Targeted Drug Delivery

In vivo Targeted Drug Delivery to the Brain using MRI Guidance of Focused Ultrasound

Introduction The clinical application of chemotherapy to brain tumors has been severely limited because antitumor agents are typically unable to penetrate an intact blood-brain barrier (BBB). Nonlocalized diffuse opening of the BBB permits drugs to reach the brain but can have dose-limiting side effects. MRI-guided focused ultrasound (FUS) can be applied to the brain to temporarily disrupt the ...

advances in targeted drug delivery

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Liver Targeted Drug Delivery System

Targeted drug delivery or site-specific drug delivery system has the potential to increase local drug concentrations and thereby increase the effectiveness of the medicines with fewer side effects. Liver diseases especially liver cancer is one of the most prevalent cancers, with a high mortality. Due to high toxicity and poor specificity of the chemotherapeutic agents the present method of trea...